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Josh Weinstock

Assistant Professor

Emory University

Biography

I am an Incoming Assistant Professor in the Department of Human Genetics at Emory University (starting Fall 2024), working at the nexus of human genetics, computation, and statistics to discover and characterize disease associated genetic variation. Previously, I was a postdoctoral scholar working jointly with Jonathan Pritchard (Stanford, Genetics) and Alexis Battle (Johns Hopkins, Biomedical Engineering), and then an Assistant Research Scientist in the Battle Lab. I completed a PhD in the Biostatistics department of the University of Michigan, where I was advised by Goncalo Abecasis. At Michigan, my contributions included analysis of somatic variation called from whole genomes generated by the NHLBI TOPMed consortium.

Interests

  • biostatistics
  • statistical genetics and genomics
  • genetic epidemiology of somatic mosaicism
  • sports statistics

Education

  • PhD in Biostatistics, 2021

    University of Michigan

  • MS in Biostatistics, 2018

    University of Michigan

  • BA in Mathematics, 2015

    Emory University

Selected Publications

Gene regulatory network inference from CRISPR perturbations in primary CD4+ T cells elucidates the genomic basis of immune disease

We mapped the gene regulatory network of key immune disease genes in primary CD4+ T cells using causal inference methods

The genetic determinants of recurrent somatic mutations in 43,693 blood genomes

We discovered thousands of unexpectedly common somatic mutations in blood

Aberrant activation of TCL1A promotes stem cell expansion in clonal haematopoiesis

We identified TCL1A as a key mediator of clonal expansion in CHIP clones

LabWAS: Novel findings and study design recommendations from a meta-analysis of clinical labs in two independent biobanks

We performed a GWAS meta-analysis of lab derived phenotypes from the Michigan Genomics Initiative (Umich) and BioVU (Vanderbilt)

Inherited causes of clonal haematopoiesis in 97,691 whole genomes

We discovered the genetic determinants of CHIP in ~97,000 TOPMed whole genomes

Contact

  • 1599 Clifton Road, NE, Atlanta, Georgia 30322